Some questions to see if anyone can help out.
1) You say "1:1 screen ratio isn't working". Does that mean that some other things are working?
2) When it stopped working, do you remember what you were doing? Did you install some new hardware / software?
3) Are you using Windows XP (SP2)?
4) You say "The drivers didn't help any either.". Does that mean that you downloaded, and installed, the latest driver from the Aiptek site?
5) My hunch is that this is a driver / software problem. Have you tried uninstalling and re-installing everything?