Roah,
(I'm going on memory on some of this, I didn't re-read 'today' all of the above posts, so I hope that I am not repeating what has been said)
I think that if you use Saturation Layer in Layer Adjustments, it'd probably benefit you by scrolling through the Blending Mode afterwards. If you highlight the "NORMAL" in Blending Mode you can then use a mouse wheel and scroll through all of the different types really quick. (I don't know what version of
PS you have though) You may already know that, but it's just another way to get brighter and different effects too, and of course, don't forget to slide the Opacity to different settings too.
You can also paint on a separate Layer colors of your choice and do the same thing, and combine colors on different Layers to, and testing the Blending Modes again. I sometimes use many Layers to get the effects I may be looking for, and 'most times' I find something unusual that I like. You may find it useful also if you scroll through the Styles at the top of Layer Styles, and experimenting with them.
You asked about "photo art", I do that all of the time, and use all of the above all of the time too.
I wouldn't consider this "art", but it was a long time ago, and I did it for fun, but I did use 'all of the above' in this.
http://4dw.net/crisp/ra/mouse.htm
Just for the record, I'm not too proud of this nowadays, I see more than a few mistakes.
I hope this stuff helps some...
Randy