Craig,
Check your IE security setting on your wifes laptop and set yours the same way. Are you running any different software on your PC then on the laptop?
I use a wired router for my home network, 3 desktops and a laptop, no problems at all. No Zone alarm or any other software, just the built in firewall on the router. I have run several port snooping software versions on my system, and none of them even see my PC's behind the firewall.
If all else fales, reset your IE settings ot default, try that, then if it still doesn't work, turn off your PC, reset the router, reboot both and try again.
HTH
Paul